SfN members conversed with their members of Congress, emphasizing that America thrives through federal investment in research.

Parkinson's disease (PD) is the most common neurodegenerative movement disorder, afflicting ∼1% of individuals over the age of 65. PD results primarily from a severe and selective devastation of dopaminergic neurons in the substantia nigra pars compacta, although neuropathology extends to other

Week of March 4, 2019: Read the Latest Advocacy and Science News

SfN continued and expanded its role as an advocate for neuroscience throughout its second 25 years, developing and refining its strategies to have the greatest impact. The initial basic goal of increased research funding developed into a wider advocacy for scientific freedom in research, in the face of political challenges such as crusades against animal research and restrictions on the use of stem cells. Lobbying at the congressional and local levels continued into the new century, including the annual "Hill Day" and meetings during legislative recess; but SfN expanded in several directions, partnering with disease advocacy groups, training young members for careers in science policy and helping international partners to develop advocacy programs in their own countries. "Over time," Nick Spitzer (Chair, Public Education and Communication Committee, 2006-09) has commented, "we have learned how to be sophisticated, how to share the message."363

Our recent work has demonstrated that the early life administration of vincristine (VNC), commonly used to treat pediatric leukemias, evokes peripheral neuropathy and mechanical pain hypersensitivity in rats that persists into adolescence. However, whet...

Chapters are able to request SfN to distribute information regarding chapter news and events to local SfN members via e-mail. E-mail Blasts traditionally include annual chapter meeting details, chapter lectures, and chapter outreach activities. Please note that all requests must be submitted by an official chapter representative or chapter officer with chapter representative approval.

Hold a presentation or product demonstration in the Product Theater*, the perfect venue for reaching hundreds of decision-makers and buyers in the Exhibit Hall. The theater is situated in a prime location on the exhibit floor, with seating for 150 people. Choose your ideal presentation time during the four days of exhibits and create a unique presentation capable of reaching a wide audience.

Hold a presentation or product demonstration in the Product Theater*, the perfect venue for reaching hundreds of decision-makers and buyers in the Exhibit Hall. The theater is situated in a prime location on the exhibit floor, with seating for 150 people. Choose your ideal presentation time during the four days of exhibits and create a unique presentation capable of reaching a wide audience.

Hold a presentation or product demonstration in the Product Theater*, the perfect venue for reaching hundreds of decision-makers and buyers in the Exhibit Hall. The theater is situated in a prime location on the exhibit floor, with seating for 150 people. Choose your ideal presentation time during the four days of exhibits and create a unique presentation capable of reaching a wide audience.

In bimanual object manipulation tasks, people flexibly assign one hand as a prime actor while the other assists. Little is known, however, about the neural mechanisms deciding the role assignment. We addressed this issue in a task in which participants moved a cursor to hit targets on a screen by applying precisely coupled symmetrical opposing linear and twist forces on a tool held freely between the hands. In trials presented in an unpredictable order, the action of either the left or the right hand was spatially congruent with the cursor movements, which automatically rendered the left or right hand the dominant actor, respectively. Functional magnetic resonance imaging indicated that the hand-selection process engaged prefrontal cortical areas belonging to an executive control network presumed critical for judgment and decision-making and to a salience network attributed to evaluation of utility of actions. Task initiation, which involved switching between task sets, had a superordinate role with refere...