The Society for Neuroscience (SfN) is pleased to recognize Abcam as the Sponsor of the Day for the second day of Neuroscience 2022, Sunday, November 13, 2022.

New neurons are produced in the hippocampal dentate gyrus throughout adulthood in rodents (for review, see [Gonçalves et al., 2016][1]; [Toda et al., 2019][2]) and likely in humans ([Boldrini et al., 2018][3]; cf. [Sorrells et al., 2018][4]). Although the total number of adult-born granule cells in

On Thursday, March 17, over 60 neuroscientists will take their message to Congress for SfN’s 10thCapitol Hill Day »

Get an inside look at SfN's Capitol Hill Day! Listen to SfN leaders, members, and students share their Hill Day experiences and explain the importance of advocating for science funding.

Neuroscience 2020 has been cancelled.

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How much we like something, whether it be a bottle of wine or a new film, is affected by the opinions of others. However, the social information that we receive can be contradictory and vary in its reliability. Here, we tested whether the brain incorporates these statistics when judging value and confidence. Participants provided value judgments about consumer goods in the presence of online reviews. We found that participants updated their initial value and confidence judgments in a Bayesian fashion, taking into account both the uncertainty of their initial beliefs and the reliability of the social information. Activity in dorsomedial prefrontal cortex tracked the degree of belief update. Analogous to how lower-level perceptual information is integrated, we found that the human brain integrates social information according to its reliability when judging value and confidence. SIGNIFICANCE STATEMENT The field of perceptual decision making has shown that the sensory system integrates different sources of i...

Debate surrounds the precise cortical location and timing of access to phonological information during visual word recognition. Therefore, using whole-head magnetoencephalography (MEG), we investigated the spatiotemporal pattern of brain responses induced by a masked pseudohomophone priming task. Twenty healthy adults read target words that were preceded by one of three kinds of nonword prime: pseudohomophones (e.g., brein –BRAIN), where four of five letters are shared between prime and target, and the pronunciation is the same; matched orthographic controls (e.g., broin– BRAIN), where the same four of five letters are shared between prime and target but pronunciation differs; and unrelated controls (e.g., lopus– BRAIN), where neither letters nor pronunciation are shared between prime and target. All three priming conditions induced activation in the pars opercularis of the left inferior frontal gyrus (IFGpo) and the left precentral gyrus (PCG) within 100 ms of target word onset. However, for the critical ...

Up to 70% of patients with Systemic Lupus Erythematosus (SLE) have deficits in cognitive functioning. These cognitive deficits have been most associated with information processing speed and working memory (WM). We hypothesized that the P3 component of the ERP, recorded during 2-back verbal and spatial WM tasks (V-WM; S-WM), would reflect processing speed and WM deficits in SLE. ERP and neuropsychological data were obtained for 16 SLE patients and 16 controls. P3 amplitudes and latencies were recorded to the first letter (prime), the middle letter (while information is held in WM) and the final letter (either a correct match with prime, GO; or not a match, NoGo) of the 2-back tasks. Results showed that for the S-WM task, controls had greater P3 amplitude than SLE patients at parietal sites for Go and NoGo, but not for the prime or the middle letter. At the frontal sites, SLE patients had greater P3 amplitude than controls for the prime and the middle letter, but not for Go and NoGo. P3 measures were also c...