Week of July 2, 2018: Read the Latest Advocacy and Science News

The Society for Neuroscience (SfN) will present the Donald B. Lindsley Prize to Kiah Hardcastle, PhD, and Christopher Zimmerman, PhD. Supported by an endowment from the Grass Foundation, the prize recognizes outstanding PhD theses in the area of general behavioral neuroscience. The $2,500 award was established in 1979 in honor of Donald B. Lindsley, an early trustee of the Grass Foundation.

Analysis of electroencephalograms is widely used in humans and animals for evaluating the type and localization of brain activation, the effects of external sensory stimulation, or the irrelevance of specific stimuli used. It has been shown that pigeons...

The Society for Neuroscience (SfN) will present four awards to leading researchers who have made significant contributions to the advancement of women in neuroscience and early-career researchers who have demonstrated great originality and creativity in their work.

Emery N. Brown, MD, PhD, will receive the 2020 Swartz Prize for Theoretical and Computational Neuroscience. The $30,000 prize, supported by the Swartz Foundation, honors an individual whose work has produced a significant cumulative contribution to theoretical models or computational methods in neuroscience or who has made a particularly noteworthy recent advance to the field.

Ischemic stroke (IS) poses a serious threat to patient survival. The inhibition of ferroptosis can effectively alleviate ischemia-reperfusion (I/R) injury, suggesting potential targets in the ferroptosis pathway for the treatment of IS. In this study, MCAO/R mice and OGD/R-induced HT22 cell were constructed. It was found that baicalein decreased ROS, MDA, and Fe2+ levels, upregulated GSH levels, and enhanced the expression of ferroptosis-related proteins (GPX4 and SLC7A11), downregulated the expression of proapoptotic proteins (Bax, cytochrome c , and cleaved caspase-3), and upregulated the expression of an antiapoptotic protein (Bcl-2), ameliorating cerebral I/R injury. In animal and cell models, Sirtuin6 (SIRT6) is downregulated, and Forkhead boxA2 (FOXA2) expression and acetylation levels are abnormally upregulated. SIRT6 inhibited FOXA2 expression and acetylation. Baicalein promoted FOXA2 deacetylation by upregulating SIRT6 expression. FOXA2 transcriptionally inhibits SLC7A11 expression. In conclusion,...

We advance and empower women in the field through resources, networking events, professional opportunities, and awards. SfN also provides the field with education to increase awareness for implicit bias.

SfN fulfills its mission to advance the understanding of the brain and the nervous system through diversity, education, outreach, career, and advocacy initiatives.

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