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SfN News News from SfNAs a leader in the scientific society community, SfN is committed to supporting discovery and scientific dialogues, and to fostering a welcoming community in which all scientists are able to contribute fully. Following discussions at the Fall meeting, SfN’s Council approved a set of changes and enhancements to SfN’s Ethics Policy and Code of Conduct.Jan 15, 2019
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The consequences of aging can vary dramatically between different brain regions and cell types. In the ventral midbrain, dopaminergic neurons develop physiological deficits with normal aging that likely convey susceptibility to neurodegeneration. While nearby GABAergic neurons are thought to be more resilient, decreased GABA signaling in other areas nonetheless correlates with age-related cognitive decline and the development of degenerative diseases. Here, we used two novel cell type-specific translating ribosome affinity purification models to elucidate the impact of healthy brain aging on the molecular profiles of dopamine and GABA neurons in the ventral midbrain. By analyzing differential gene expression from young adult (7-10 months) and old (21-24 months) mice, we detected commonalities in the aging process in both neuronal types, including increased inflammatory responses and upregulation of pro-survival pathways. Both cell types also showed downregulation of genes involved in synaptic connectivity ...May 1, 2025
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AbstractThe ability to register data from freely moving imaging experiments to data from high resolution confocal or multi-photon imaging will begin to provide crucial links between activity dynamics and anatomical, molecular, and/or connectivity profiles of di...Oct 22, 2019
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SfN News Meetings Press ReleaseThe Society for Neuroscience (SfN) has awarded The Peter and Patricia Gruber International Research Award in Neuroscience to Shantanu P. Jadhav, PhD, of the University of California, San Francisco (UCSF), and Dengke K. Ma, PhD, of the Massachusetts Institute of Technology (MIT). The award recognizes two promising young scientists for outstanding research and educational pursuit in an international setting. It is supported by The Gruber Foundation and includes $25,000 for each recipient. The award was presented during Neuroscience 2013, SfN’s annual meeting and the world’s largest source of emerging news about brain science and health.Oct 31, 2013
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