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Animal Models

Even animals with simple nervous systems can help us learn about how our own nervous system works.

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Introduction

Neuroscientists aim to understand how the brain works and to advance treatments for diseases and disorders of the nervous system. This type of research requires investigating complex functions at all levels of the living nervous system. Because it is impossible to use humans for this work, neuroscientists turn to animals. Acting under regulations put forth by governmental agencies, scientists use animals to discover how diseases and their potential therapies affect the entire body — experimental procedures that are often difficult, if not impossible, to replicate with alternative methods.

Discoveries

Animal Research Success: Blindness and the Retina

Source: Society for Neuroscience
Research on dogs has enabled scientists to develop a potential cure that could someday restore vision to people – and dogs – with leber congenital amaurosis.

Animal Research Success: Drug Addiction

Source: Society for Neuroscience
Animal research has helped scientists better understand how repeated drug use changes the brain, resulting in new treatments for addiction.

Animal Research Success: Prion Diseases

Source: Society for Neuroscience
There is no cure for prion diseases, such as "mad cow" disease, however, researchers’ increased understanding of these diseases has had positive benefits for both humans and animals.

Animal Research Success: Stroke

Source: Society for Neuroscience
There is only one established clinical treatment for stroke, which was developed following experiments observing stroke in rabbits.

Animal Research Success: Psychiatric Disorders

Source: Society for Neuroscience
Animal models have been central to the discovery of drug treatments for such serious disorders as depression, anxiety disorders, and schizophrenia.

Animal Research in the News

'Master Gene' Makes Mouse Brain Look More Human

Source: Science
Date: 25 April 2013
A genetic mutation that causes mammalian neural tissue to expand and fold may help explain why humans evolved more elaborate brains than mice.

Scientists Puzzle Over How Bat Brains and Rat Brains Build Mental Maps

Source: MSNBC
Date: 18 April 2013
By studying the brain activity, researchers hoped to uncover clues about how many mammals, not just bats, know where they are.

Yorkshire Pigs Control Computer Gear With Brain Waves

Source: WIRED
Date: 5 March 2013
Wouldn’t it be great if you could control your PC with your brain? Well, this sort of thing may be closer than you think.