Neuroscience 2001 Abstract
Presentation Number: | 639.14 |
---|---|
Abstract Title: | THE CONTROL OF MEMORY: A FUNCTIONAL MAGNETIC RESONANCE IMAGING STUDY ON THE INFLUENCE OF TASK SET IN HUMAN PREFRONTAL CORTEX. |
Authors: |
Speer, N. K.*1
; Braver, T. S.1
; Jacoby, L. L.1
1Department of Psychology, Washington University, St. Louis, MO |
Primary Theme and Topics |
Cognition and Behavior - Human Cognition and Behavior -- Learning and memory |
Session: |
639. Human cognition and behavior: learning and memory IX Poster |
Presentation Time: | Tuesday, November 13, 2001 2:00 PM-3:00 PM |
Location: | Exhibit Hall SS-47 |
Keywords: | WORKING MEMORY, LONG-TERM MEMORY, NEUROIMAGING, STRATEGY |
In this study we were interested in the hypothesis that different task sets would influence both behavior and prefrontal cortex (PFC) activation during performance of a memory task. Specifically, participants were asked to remember a list of words over a short delay, and then respond to a probe word, indicating whether or not the probe was present in the list of words. In one condition, participants were encouraged to use an active maintenance strategy by presenting short lists of words (1 to 6 words per list). In the other condition, participants were encouraged to use a retrieval-based strategy by presenting long lists of words (6 to 11 words per list). The critical comparison is between the 6-word trials, since the memory load, trial duration, and perceptual input are identical across the two conditions. To test our hypothesis that activation in PFC would correlate with task set, we conducted an event-related functional magnetic resonance imaging (fMRI) study on 25 younger adults. Behavioral results confirmed our hypothesis that both accuracy and reaction time would differ between the two tasks and the critical trials. Time courses of activation in PFC for the 6-word trials presented in the context of the short list task were compared with those presented in the context of the long list task. Significant differences in the pattern of activation in response to the 6-word trials were observed bilaterally in dorsolateral and ventrolateral PFC (BA 46/9, 47), as well as in right frontopolar cortex (BA 10). These results are discussed in terms of their relationship to specific memory strategies.
Supported by NIH grant MH61615-02
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online.
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