Neuroscience 2000 Abstract
| Presentation Number: | 594.8 |
|---|---|
| Abstract Title: | A discrete region of the human insular cortex responds to odorant stimuli: a functional magnetic resonance imaging study. |
| Authors: |
Nunez, J. M.*1
; Hirsch, J.2
1Department of Neurology and Neuroscience, Cornell University, Weill Medical College, New York, NY 2Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY |
| Primary Theme and Topics |
F. Sensory Systems - 84. Chemical senses |
| Secondary Theme and Topics | F. Sensory Systems<br />- 85. Multisensory processing |
| Session: |
594. Chemical senses: imaging Slide |
| Presentation Time: | Wednesday, November 8, 2000 9:45 AM-10:00 AM |
| Location: | Room 291 |
| Keywords: | OLFACTION, FMRI, INSULA, HUMAN |
The insular cortex receives direct connections from primary olfactory structures such as the piriform cortex, anterior olfactory nucleus and primary olfactory bulb. Based upon these connections an olfactory related function within the insular cortex would be expected, yet such a relationship has not been clearly characterized. Using whole brain fMRI, we have identified a discrete region of the human posterior insular cortex which responds to different olfactory stimuli over successive exposures both within and between experimental sessions. Further, this activity appears highly dependent upon the number of odorant exposures and the length of time between odorant exposures, possibly reflecting habituation at a hemodynamic and presumably neural level. We propose that this olfactory-responsive region of the posterior insular cortex performs a previously unrealized role in olfaction and the insular cortex may be a key player in olfactory related sensation. This work was supported by the Cornell/Rockefeller/Sloan-Kettering Tri-Institutional M.D./Ph.D. program; NIH MSTP grant GM07739; Charles A. Dana Foundation; Johnson & Johnson Focused Giving Foundation; and the Cancer Center Support Grant, CI-P30-CA-08748.
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online.
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