Neuroscience 2005 Abstract
| Presentation Number: | 410.15 |
|---|---|
| Abstract Title: | The cortical correlates of swallowing planning and execution: a functional magnetic resonance imaging (fMRI) study. |
| Authors: |
Toogood, J. A.*1
; Smith, R. C.2
; Stevens, T. K.3
; Gati, J. S.
; Menon, R. S.1,3
; Martin, R. E.1,2
1Graduate Program in Neuroscience, Univ. of Western Ontario, London, Canada 2School of Communication Sciences and Disorders, Univ. of Western Ontario, London, Canada 3Medical Biophysics, Univ. of Western Ontario, London, Canada |
| Primary Theme and Topics |
Cognition and Behavior - Human Cognition, Behavior, and Anatomy -- Anatomy |
| Secondary Theme and Topics | Sensory and Motor Systems<br />- Tactile/Somatosensory<br />-- Thalamus and Cortex |
| Session: |
410. Anatomy and Individual Differences Poster |
| Presentation Time: | Monday, November 14, 2005 10:00 AM-11:00 AM |
| Location: | Washington Convention Center - Hall A-C, Board # EE20 |
| Keywords: | CORTEX, SENSORIMOTOR, BRAIN IMAGING, MOTOR CONTROL |
Brain-imaging studies have shown that voluntary swallowing activates a distributed network of cortical regions including the lateral sensorimotor cortex, anterior cingulate cortex (ACC), insula and operculum. Previous research has implicated these regions in both planning and execution of voluntary motion. Therefore, the present study sought to differentiate the functional contributions of these foci in the (1) planning, and (2) execution of voluntary saliva swallowing. The experiment consisted of a delayed response task in which a visual cue instructing the subject to prepare to swallow was presented 10-12 seconds prior to a second visual cue instructing the subject to swallow. Seven healthy subjects (mean age = 27.7 ± 3.4 years) performed the task while laryngeal movement data were simultaneously recorded to verify swallowing events. Contrast analyses indicated that activations within the lateral sensorimotor cortex and ACC were significantly greater (pcorrected < 0.01) during swallowing planning than during swallowing execution, whereas activation within the insula and operculum was significantly greater (pcorrected < 0.01) during swallowing execution than during swallowing planning. These findings support the view that discrete foci within the swallowing neural network make functionally distinct contributions to swallowing, with some areas mediating swallowing planning and others regulating swallowing execution. They may also explain inconsistencies across previous swallowing studies, as well as the variety of swallowing deficits observed following hemispheric stroke.
Supported by Heart and Stroke Foundation of Ontario, Natural Sciences and Engineering Research Council of Canada
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online.
Copyright © 2005-2025 Society for Neuroscience; all rights reserved. Permission to republish any abstract or part of any abstract in any form must be obtained in writing by SfN office prior to publication.
