Neuroscience 2000 Abstract
| Presentation Number: | 385.13 |
|---|---|
| Abstract Title: | Using neuropsychological tests and magnetic resonance imaging to identify memory deficits and changes in brain morphology in women suffering from posttraumatic stress disorder secondary to child abuse. |
| Authors: |
Pederson, C. L.*1
; Maurer, S. H.1
; Zander, K. A.1
; Osborn, R.3
; Kaminski, P. L.2
1Biology, Wittenberg University, Springfield, OH 2Psychology, Wittenberg University, Springfield, OH 3Radiology, Mercy Medical Center, Springfield, OH |
| Primary Theme and Topics |
J. Disorders of the Nervous System and Aging - 140. Neuropsychiatric disorders |
| Secondary Theme and Topics | I. Neural Basis of Behavior<br />- 102. Cognition: human learning and memory |
| Session: |
385. Neuropsychiatric disorders: neural pathways Poster |
| Presentation Time: | Monday, November 6, 2000 1:00 PM-2:00 PM |
| Location: | Hall G-J |
| Keywords: | Hippocampus, Auditory memory, Trauma, Humans |
Childhood abuse is increasingly linked to Posttraumatic Stress Disorder (PTSD), a mental affliction which follows abuse survivors into adulthood. All subjects were right handed women between the ages of 20 and 40 who fit into one of three groups: 1. History of childhood abuse resulting in PTSD, 2. History of childhood abuse not resulting in PTSD, and 3. No history of abuse. Each subject was screened for trauma history and personality disorders using the Childhood Trauma Questionnaire, Trauma Symptoms Inventory, and Million Clinical Multiaxial Inventory: Third Edition. Each subject was clinically interviewed to confirm group assignment and given the Weschler Memory Scales, Wonderlic Personnel Test (IQ), and a magnetic resonance imaging (MRI) scan of her brain. Subjects were demographically matched into triads based on group assignment, age, education, and use of alcohol, nicotine, and prescription medications. While there were no significant differences between groups demographically, women in Group 1 demonstrated significant deficits in auditory immediate memory (p<.02) when compared with Groups 2 and 3. Interestingly, Group 1 did not have a significant deficit in auditory delayed memory. In addition, MRI data indicated left hippocampal atrophy in Group 1 when compared with Groups 2 and 3. These results indicate that women with PTSD express deficits in auditory immediate memory which may be linked to atrophy in the left hippocampus.
Supported by Wittenberg Faculty Research Fund Board and MacGregor Grant
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online.
Copyright © 2000-2025 Society for Neuroscience; all rights reserved. Permission to republish any abstract or part of any abstract in any form must be obtained in writing by SfN office prior to publication.
