Neuroscience 2004 Abstract
| Presentation Number: | 300.14 |
|---|---|
| Abstract Title: | Loop and linear connections in high-order human occipito-temporal cortex. |
| Authors: |
Kim, M.*1
; Ducros, M.
; Carlson, T.
; He, S.
; Ugurbil, K.1
; Kim, D. S.1
1Ctr. for Magnetic Resonance Res., Univ. of Minnesota, Minneapolis, MN |
| Primary Theme and Topics |
Sensory Systems - Vision -- Visual cortex: Functional organization and circuitry |
| Session: |
300. Visual Cortex: Organization and Circuitry Poster |
| Presentation Time: | Sunday, October 24, 2004 2:00 PM-3:00 PM |
| Location: | San Diego Convention Center - Hall A-H, Board # S7 |
| Keywords: |
Although a large number of categories and category classes represented along the ventral stream have been found in the human visual system, it has been difficult to outline the anatomical circuitry underlying the receptive field properties of object selective neurons due to the lack of non-invasive techniques. Here, the relationship between functional activity and neuronal connectivity across the striate and extrastriate cortical areas were investigated. Neuronal connections between areas of different receptive field properties were assessed in vivo using the Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) in combination with functional magnetic resonance imaging (fMRI). DTI in conjunction with functional MRI was performed using a 3 Tesla whole body scanner (Trio, Siemens). Functional imaging scans were used to localize retinotopic and non-retinotopic visual areas in healthy human volunteers. BOLD contrast was obtained using gradient-echo echo-planar imaging (EPI) sequence (30 axial slices of 2-mm thickness). For DTI, diffusion-weighted images (DWI) with 12 gradient encoding directions were acquired from the same subjects by spin-echo EPI. T1-weighted high resolution anatomical images were also obtained for each subject to allow accurate cortical alignment and segmentation. The results of our study suggest that the human ventro-temporal visual areas are interlinked by a loop-like and a linear connectivity. Furthermore, the presence of a putative “trans-stream” communication channel was found between the ventral and the dorsal streams prior the converging pathways in prefrontal and parahippocampal cortices.
Supported by NIH (RR08079), the Keck Foundation, and the Human Frontiers Science Program
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online.
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