Neuroscience 2003 Abstract
| Presentation Number: | 69.19 |
|---|---|
| Abstract Title: | Functional MRI in behaving monkeys. |
| Authors: |
Pinsk, M. A.*1
; Moore, T.2
; Richter, M.1
; Gross, C. G.2
; Kastner, S.1
1Dept. of Psychology, CSBMB, Princeton Univ., Princeton, NJ 2Green Hall, 08544, |
| Primary Theme and Topics |
Sensory Systems - Vision -- Visual cortex: Functional organization and circuitry |
| Session: |
69. Imaging Visual Cortex Poster |
| Presentation Time: | Saturday, November 8, 2003 3:00 PM-4:00 PM |
| Location: | Morial Convention Center - Hall F-I, Board # H22 |
| Keywords: | FMRI, Monkey, Vision |
Comparisons of neural activity between humans and monkeys have usually relied on techniques using very different spatial and temporal scales. We report a method for scanning behaving macaques in a horizontal human 3 Tesla MR scanner to investigate neural processes involved in perception and to compare them to that of humans. Specifically, we have developed an apparatus for the animal to lie prone in the scanner bore, training procedures to minimize body movements while maintaining long periods of eye fixation (> 10 s), a mock training environment to acclimate the animal to the sights and sounds of the MRI, and surgical head-bolt implants for rigid head fixation that are MR-compatible. With the use of a 12 cm surface coil placed above the animal’s head, high-resolution functional (1.5 x 1.5 x 2.0 mm) and anatomical (0.5 mm3) scans are acquired in awake animals. Ongoing studies are exploring the organization of inferior temporal cortex with direct comparisons to human cortex. Other studies map retinotopically organized visual areas onto 3D anatomical surface reconstructions to investigate substrates of visual recovery following striate cortex damage.
Supported by NSF, NIH
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2003 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2003. Online.
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