Neuroscience 2001 Abstract
| Presentation Number: | 855.4 |
|---|---|
| Abstract Title: | Comparative Atlases of Great Ape Brains from Magnetic Resonance Images. |
| Authors: |
Ely, J. J.*1,7
; Sherwood, C. C.2
; Delman, B. N.4
; Gentile, J. C.4
; Naidich, T. P.4
; Perl, D. P.5,7
; Gannon, P. J.6
; Erwin, J. M.1,7
; Hof, P. R.3,7
1Bioqual Inc, Rockville, MD 2Anthropology, Columbia University, NY, NY 3Neurobiology, Mount Sinai School of Medicine, NY, NY 4Radiology, Mount Sinai School of Medicine, NY, NY 5Pathology, Mount Sinai School of Medicine, NY, NY 6Otolaryngology, Mount Sinai School of Medicine, NY, NY 7Foundation for Conservation and Comparative Biology, Blacksburg, VA |
| Primary Theme and Topics |
Cognition and Behavior - Neuroethology |
| Session: |
855. Neuroethology: comparative anatomy and brain evolution Poster |
| Presentation Time: | Wednesday, November 14, 2001 4:00 PM-5:00 PM |
| Location: | Exhibit Hall UU-21 |
| Keywords: | comparative anatomy, brain evolution, primate, aging |
Magnetic resonance imaging (MRI) is a valuable technique in the study of comparative neuroanatomy. MRIs allow visualization of the brain¹s structures in normal three-dimensional (3D) arrangement while avoiding the accumulation of artifacts associated with histological procedures. Additionally, 3D MRI datasets are compatible with geometric morphometric analyses not possible with histological samples. The Great Ape Aging Project, a comparative neurobiology of aging resource, has collected over 50 brain specimens of great apes on loan from zoological gardens and research centers. Using a 1.5 Tesla MRI scanner, high-resolution T1 and T2 weighted scans of postmortem brains (age range=19-51) from chimpanzees (n=10), gorillas (n=2), and orangutans (n=2) have been obtained in axial, coronal, and sagittal planes. 3D surface reconstructions have also been made. The high quality of these materials permitted the development of MRI-based brain anatomic atlases in these species with a high level of spatial resolution. These MRI scans will also be used in conjunction with cyto- and myeloarchitectural preparations to create correlative atlases of great ape brains. Such atlases will be useful for comparative studies of rare species for which only scarce data are available from the literature and will provide a valuable resource to investigate the effects of aging on the brain of long-lived primates closely related to humans.
Supported by Bioqual Inc., FCCB, NYCEP, MSSM, NIH (AG14308), and NSF.
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online.
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