Neuroscience 2004 Abstract
| Presentation Number: | 642.1 |
|---|---|
| Abstract Title: | Discrete functional contributions of cerebral cortical foci in voluntary swallowing: a functional magnetic resonance imaging (fMRI) 'Go, No-Go' study. |
| Authors: |
Toogood, J. A.*1,2
; Barr, A. M.2
; Stevens, T. K.4
; Gati, J. S.
; Menon, R. S.1,3
; Martin, R. E.1,2,3
1Neurosci., Univ. Western Ontario, London, Canada 2ON, Elborn College 2528, N6G 1H1, 3Canada, Elborn College 2528, N6G 1H1, 4Communication Sci. and Disorders, Elborn College 2528, N6G 1H1, |
| Primary Theme and Topics |
Sensory Systems - Tactile/Somatosensory -- Cortex imaging |
| Session: |
642. Cortex Imaging I Poster |
| Presentation Time: | Tuesday, October 26, 2004 8:00 AM-9:00 AM |
| Location: | San Diego Convention Center - Hall A-H, Board # W5 |
| Keywords: | BRAIN IMAGING, CORTEX, SENSORIMOTOR, NEUROIMAGING |
Brain-imaging studies have shown that visually-cued, voluntary swallowing activates a distributed network of cortical regions including the precentral and postcentral gyri, anterior cingulate cortex (ACC), insula, frontoparietal operculum, cuneus and precuneus. To elucidate the functional contributions of these discrete activation foci for swallowing, a “Go, No-Go” functional magnetic resonance imaging (fMRI) paradigm was designed. Brain activation associated with visually-cued swallowing was compared with brain activation evoked by a comparable visual cue instructing the subject not to swallow. Region-of-interest analyses performed on data from 8 healthy subjects showed a significantly greater number of activated voxels within the precentral gyrus, postcentral gyrus, and ACC during the “Go” condition compared to the “No-Go” condition. This finding suggests that the precentral gyrus, postcentral gyrus, and ACC contribute primarily to the act of swallowing. In contrast, the numbers of activated voxels within the cuneus and precuneus were not significantly different for the “Go” and “No-Go” conditions, suggesting that these regions mediate processing of the cue to swallow. Together these findings support the view that the discrete cortical foci previously implicated in swallowing mediate functionally distinct components of the swallowing act.
Supported by Ontario Ministry of Health and Long-Term Care, NSERC, CIHR
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online.
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