Neuroscience 2001 Abstract
| Presentation Number: | 680.14 |
|---|---|
| Abstract Title: | FMRI of visual motion and visual motion after effect in the awake behaving macaque. |
| Authors: |
Dubowitz, D. J.*1
; Bernheim, K. A.1
; Andersen, R. A.1
1Biology, Caltech, Pasadena, CA |
| Primary Theme and Topics |
Sensory Systems - Vision -- Extrastriate visual cortex: Funtional organization and circuitry |
| Secondary Theme and Topics | Sensory Systems<br />- Vision<br />-- Extrastriate visual cortex: Motion and depth |
| Session: |
680. Vision: extrastriate visual cortex--motion and depth II Slide |
| Presentation Time: | Wednesday, November 14, 2001 11:15 AM-11:30 AM |
| Location: | Room 11B |
| Keywords: | VISION, EXTRASTRIATE CORTEX, IMAGING, FUNCTIONAL MRI |
The use of macaques for functional magnetic resonance imaging of cortical activation during a cognitive task requires extensive behavioral training. We describe our success in training a macaque to lie motionless within a conventional MRI scanner and fixate on a point at the center of a 22 degree visual stimulus for extended periods of time, during which we observed stimulus-correlated activation of cortex.
The experiments used BOLD and iron oxide (CBV-sensitive) techniques. Visual stimuli were presented to the animal while eye position was maintained within a 4 degree deviation for the duration of the stimulus (~30 sec).
We were able to assess the distribution of cortical areas sensitive to visual motion and the visual motion after effect (MAE). In response to a stimulus of contracting concentric circles (CC) followed by stationary CC, a region within the superior temporal sulcus corresponding to area MT is activated (see figure). The time course of this response shows activity during both the contracting and stationary phases. A stimulus of expanding and contracting CC followed by stationary CC yields only a single period of activity correlated with the moving phase of the stimulus. This difference suggests that the second period of activation in area MT is due to the perception of the MAE.
The experiments used BOLD and iron oxide (CBV-sensitive) techniques. Visual stimuli were presented to the animal while eye position was maintained within a 4 degree deviation for the duration of the stimulus (~30 sec).
We were able to assess the distribution of cortical areas sensitive to visual motion and the visual motion after effect (MAE). In response to a stimulus of contracting concentric circles (CC) followed by stationary CC, a region within the superior temporal sulcus corresponding to area MT is activated (see figure). The time course of this response shows activity during both the contracting and stationary phases. A stimulus of expanding and contracting CC followed by stationary CC yields only a single period of activity correlated with the moving phase of the stimulus. This difference suggests that the second period of activation in area MT is due to the perception of the MAE.
Supported by Supported by NIH grants GM08042&EY07492 and a JG Boswell Professorship
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online.
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