Functional magnetic resonance imaging (fMRI) studies show increases in the blood oxygenation level dependent (BOLD) response in corticothalamic networks in absence epilepsy. However, decreases of the BOLD response also occur, but are poorly understood. ...

Recent functional magnetic resonance imaging (fMRI) studies have shown that low-frequency fluctuations in blood oxygenation level-dependent (BOLD) signals during rest periods reflect self-organized patterns of ongoing activity across large-scale distrib...

There is increased interest in using functional magnetic resonance imaging (fMRI) to study functional differentiation within the human hippocampus and nearby structures in the medial temporal lobe (MTL) memory system. However, conventional approaches to...

Read advocacy news from the week of October 7, 2016

Neuroanatomy is currently studied at orders of magnitude disparate resolutions and volumes: from nanometer reconstructions of small volumes of brains with electron microscopy to millimeter voxel resolution maps of whole brains with magnetic resonance im...

Stroke is a leading cause of adult disability and strategies to improve motor recovery are vital. Real-time functional magnetic resonance imaging (fMRI) neurofeedback aims to drive brain activation towards optimal patterns through online feedback. The p...

To make sense of the world, it is necessary to segment our ongoing stream of experience into unique events i.e. event segmentation. One approach to studying event segmentation uses functional magnetic resonance imaging (fMRI) responses while participant...

How are sounds represented in the human brain? Here we use similarity-based fusion of human magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) responses from sounds of human voices, animals, objects, and spaces to resolve the ...

Neurological disease drives symptoms through pathological changes to circuit functions. Therefore, understanding circuit mechanisms that drive behavioral dysfunction is of critical importance for quantitative diagnosis and systematic treatment of neurological disease. Here, we describe key technologies that enable measurement and manipulation of neural activity and neural circuits. Applying these approaches led to the discovery of circuit mechanisms underlying pathological motor behavior, arousal regulation, and protein accumulation. Finally, we discuss how optogenetic functional magnetic resonance imaging reveals global scale circuit mechanisms, and how circuit manipulations could lead to new treatments of neurological diseases.

Real-Time Functional Magnetic Resonance Imaging (rt-FMRI) neurofeedback is a non-invasive neuroimaging technique that allows subjects to gain control of their brain responses via online feedback of neuronally induced local changes in blood oxygenation (...