In order to assess the role of striatal neurons in sequential movement, we applied mutual information analysis of single neuron activity of the primate putamen, reported in (Ueda and Kimura, Abst. of SfN 1999,765.17). In each trial, monkeys (macaca fuscata) first (Ins-task) turned a lever either to the right or to the left from a control hold position, then turned the lever or pressed a button in the opposite side under visual guidance. Subsequently (Rem-task) the same sequence of movement was performed without visual guidance but with auditory timing cues. We performed mutual information analysis (Sugase et.al. 1999) on 90 putamen neurons. The information about the first movement direction, left-right (LR) information, during 200ms before and 100ms after the lever movement completion was 8.1 bit in Ins-task and 5.9 bit in Rem-task (sum over neurons with significant information). The LR-information during 200-400ms before the first cue was 1.8 bit in Rem-task, while it was insignificant in Ins-task. The LR...