Prepare now and beat the rush when abstract submission opens.

Background: The incidence of delirium is high in ICU as 20~40%, and it is a risk factor to increase the duration of a hospital stay, morbidity, and mortality. However delirium tends to have been overlooked compared to other medical and surgical conditio...

On the 50th anniversary of the Society for Neuroscience, we reflect on the remarkable progress that the field has made in understanding the nervous system, and look forward to the contributions of the next 50 years. We predict a substantial acceleration of our understanding of the nervous system that will drive the development of new therapeutic strategies to treat diseases over the course of the next five decades. We also see neuroscience at the nexus of many societal topics beyond medicine, including education, consumerism, and the justice system. In combination, advances made by basic, translational, and clinical neuroscience research in the next 50 years have great potential for lasting improvements in human health, the economy, and society.

As you move through an environment, the positions of surrounding objects relative to your body constantly change. Updating these locations is of major importance whenever objects go out of view, or when, like pilots and firefighters, people operate in s...

We look forward to welcoming attendees to the in-person experience in Chicago November 13-16 for SfN’s 50th annual meeting. Due to COVID-19 there are uncertainties regarding travel. Please consult the travel resources listed below in order to help plan your trip. Consistent with national and international public health guidance, SfN strongly recommends all of those planning to attend Neuroscience 2021 to be fully vaccinated if possible, subject to the advice of their personal physician. SfN expects all in-person attendees of Neuroscience 2021 to assess and implement for themselves all local, national, and international safety protocols to ensure the most productive and healthiest in-person meeting.

NW Noggin is a nonprofit integrative art and neuroscience organization that takes an innovative approach to education for people of all ages. Noggin operates through the combined effort of students, scientists, and artists from Oregon and Washington Sta...

Social animals compete for rewards to survive, yet the neural circuits underlying reward-based social competition remain unclear. The medial prefrontal cortex (mPFC) plays a key role in reward processing and social dominance, but whether its subregions contribute differently to competitions for reward remains unknown. Using c-Fos mapping in male CD1 mice, we examined reward-induced neural activation in mPFC subregions and key interconnected subcortical areas across social and non-social reward contexts. Non-competitive social contexts produced global c-Fos activation relative to competitive contexts. Cross-regional correlation analyses revealed that receiving rewards in isolation involved widespread network coordination, while social contexts exhibited distinct, sparse correlation patterns. Surprisingly, social rank effects on neural activity were most pronounced during isolated reward experiences rather than during competition, with dominant mice showing increased anterior cingulate, basolateral amygdala,...

Poor functional recovery after peripheral nerve injury is attributable, at least in part, to chronic motoneuron axotomy (Fu & Gordon, JNS 15:3876,1995) and chronic Schwann cell (SC) denervation (Sulaiman & Gordon, JNS: submitted). FK506 accelerates the rate of nerve regeneration following sciatic nerve crush or immediate nerve repair via an action involving FKBP-52, a chaperone component of mature steroid receptor complexes (Gold et al., JPET 289:1202, 1999). However, for clinical application, it is important to determine whether FK506 is effective after chronic nerve injuries. Following 2 months chronic injury of adult rat proximal tibial (old TIB; chronic axotomy) or distal common peroneal (old CP; chronic SC denervation), old TIB-freshly cut distal CP or freshly cut TIB-old CP cross-sutures were performed and rats were given subcutaneous injections of FK506 (5mg/kg/day) for 3 weeks. In the chronic axotomy model, FK506 doubled the number of regenerated motoneurons identified by retrograde labeling and in...

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