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  • Abstract
    Increased expression of the GDNF receptor GFRα1 in trans in the striatum of double transgenic mice (CAMKII -tTA X BiTetO-LacZ-rGFRα1): Neuroprotective effects in the intrastriatal 6-hydroxydopamine model of Parkinson’s disease
    Glial cell line-derived neurotrophic factor (GDNF) protects and restores dopamine (DA) neurons of the substantia nigra (SN) in a variety of models of parkinsonism. These effects of GDNF are mediated by the GDNF family receptor α1 (GFRα1) through its int...
    Nov 7, 2007
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