There is currently a large difficulties in diagnostic in children who present with loss of consiousness, falls or other paroxysmal motor phenomena. However in 10-20% of children with paroxysmal disorders the epilepsy develops in several months later. The mechanisms of these injuries are currently not well understood. Glutamate-calcium cascade can play the important role in these disorders. It was shown that a damage of glutamatergic neurons results in the appearanse of autoantibodies (aAB) to glutamate (AMPA) receptors. Previously we established increase of the aAB level in children with epilepsy (ELISA method) (SFN abstracts, 1996). The objective of the present work was to estimate the aAB level in children with different non-epileptic fits. The aAB level was the greatest in 74% children with febrile convulsions (FC). In 21% of children with FC having the high level of aAB the convulsions were repeated. We supposed that the damages of glutamate receptors in FC responsible for the mesial-temporal scleroses...