Neuroscience 2002 Abstract
| Presentation Number: | 583.9 |
|---|---|
| Abstract Title: | Neural interactions between semantic processing and working memory: A functional magnetic resonance imaging study. |
| Authors: |
D'Arcy, R. C. N.*1
; Ryner, L.1
; Richter, W.2
1Natl Res Council Canada, Inst Biodiagnostics, Winnipeg, Canada 2Chemistry, Center for the Study of Brain, Mind, and Behavior, Princeton, NJ |
| Primary Theme and Topics |
Cognition and Behavior - Human Cognition and Behavior -- Language |
| Secondary Theme and Topics | Cognition and Behavior<br />- Human Cognition and Behavior<br />-- Executive function: Working memory |
| Session: |
583. Human cognition and behavior: language III Poster |
| Presentation Time: | Tuesday, November 5, 2002 1:00 PM-2:00 PM |
| Location: | Hall A2-B3 R-15 |
| Keywords: | BRAIN IMAGING, COGNITION, FUNCTIONAL MRI, EVOKED POTENTIALS |
We studied the effects of working memory (WM) on semantic neural systems using event-related functional magnetic resonance imaging (fMRI). Semantic congruency was manipulated using a series of visual sentence pairs with predictable endings. In each pair, the first sentence primed contextual expectation for the terminal word in the second sentence. The second sentence ended with either a semantically appropriate or a semantically inappropriate ending. WM was manipulated by increasing the memory set size. Level 1 WM load contained a single prime sentence and Level 2 contained two prime sentences. Task related activation occurred predominately in the left hemisphere and increased as a function of WM load. Interactions between semantic processing and WM effects were examined within the inferior parietal, superior temporal, lateral frontal, and cingulate regions. The correspondence between the current fMRI results and prior work on the manner in which WM influences the semantic N400 response was examined. Overall, the hemodynamic and electromagnetic findings revealed a clear spatio-temporal interaction between semantic processing and WM.
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2002 Neuroscience Meeting Planner. Orlando, FL: Society for Neuroscience, 2002. Online.
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