Neuroscience 2000 Abstract
| Presentation Number: | 560.10 |
|---|---|
| Abstract Title: | Anticipatory musical imagery: a functional MRI study. |
| Authors: |
Van Lare, J. E.*1
; Zielinski, B. A.1
; Rauschecker, J. P.1
1Georgetown Institute for Cognitive and Computational Sciences, Georgetown University Medical Center, Washington, DC |
| Primary Theme and Topics |
I. Neural Basis of Behavior - 105. Cognition: higher functions |
| Session: |
560. Cognition: higher functions II Poster |
| Presentation Time: | Tuesday, November 7, 2000 2:00 PM-3:00 PM |
| Location: | Hall G-J |
| Keywords: | Auditory perception, Memory , FMRI , Music |
Repeated listening to a series of sound tracks in the same sequence creates a long-lasting sequential auditory memory. Listening to the end of a track immediately evokes an auditory image of the beginning of the next track. We have studied the functional anatomy of this anticipatory musical imagery with functional magnetic resonance imaging (fMRI). Subjects were screened for the reliability of their anticipatory imagery using sound tracks from their favorite compact disk. Each subject listened to the final 32 sec of each track in random order and was asked to produce the opening bars of the following track. Only subjects who scored above 75% correct were used for further study. Each fMRI scan consisted of nine 40-sec cycles divided into 32 sec of song followed by 8 sec of silence. Each imaging session included six functional scans alternating between familiar and unfamiliar song sets. Activation during silent anticipation of the next track following familiar songs (familiar silence) was compared with that following unfamiliar songs (unfamiliar silence). While subjects listened to the actual music, whether familiar or unfamiliar, extensive regions of superior temporal cortex in both hemispheres were reliably activated. Familiar music additionally activated the precuneus region. By contrast, during familiar but not during unfamiliar silence, subjects demonstrated highly significant activation in the anterior superior temporal, anterior insular and inferior frontal cortex of the right hemisphere, in dorsolateral prefrontal cortex of the left hemisphere, and in the cerebellum bilaterally. Individual subjects also activated the anterior cingulate region. These results suggest that anticipation of familiar music engages auditory memory systems in the cerebral cortex. Whereas perception and recall of music has been associated with a right-hemisphere bias, activation of left prefrontal cortex is consistent with certain forms of semantic memory retrieval. Activation of the cerebellum further corroborates its postulated role in higher cognitive processes. The anticipatory activation of these brain regions may be important during musical recital from memory, invoking top-down processing that enables a direct matching of the sensory evoked activity with the stored image in the mind’s ear.
Supported by DAMD17-93-V-3018 and by NIDCD grant R01-DC-03489 to J.P.R.
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online.
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