Neuroscience 2000 Abstract
| Presentation Number: | 176.6 |
|---|---|
| Abstract Title: | Phasic and tonic neuronal responses related to behavioral persistence during multitrial reward schedules in monkey anterior cingulate. |
| Authors: |
Shidara, M.*1
; Richmond, B. J.2
1Neurosci Sect., Electrotechnical Lab., Tsukuba-shi, Japan 2Lab. of Neuropsychol., NIMH, Bethesda, MD |
| Primary Theme and Topics |
I. Neural Basis of Behavior - 110. Motivation and emotion |
| Secondary Theme and Topics | I. Neural Basis of Behavior<br />- 107. Learning and memory: systems and functions-animals |
| Session: |
176. Motivation and emotion III Poster |
| Presentation Time: | Sunday, November 5, 2000 2:00 PM-3:00 PM |
| Location: | Hall G-J |
| Keywords: | multiple trial schedule, anterior cingulate, single unit activity, rhesus monkey |
Anterior cingulate cortex (area 24c) is part of an anatomical loop including ventral striatum, ventral pallidum, and mediodorsal thalamus that is important for generating behavior related to motivationally or emotionally important stimuli. We reported that many neurons in the anterior cingulate have phasic responses to specific events in multitrial reward schedules (SFN abstr, 99). Two rhesus monkeys are taught to release their grip on a bar when a visual target changes from red to green. Then they are exposed to schedules requiring 1, 2, 3, or 4 correct trials to obtain a reward. A rectangle, acting as a cue to the schedule, is located above the target. This cue brightens as the trial comes closer to the rewarded one, being brightest when correct completion of the current trial will leads to reward. Behavioral errors and reaction times decreased as the reward approached. About 80% (52/61) of the recorded neurons responded during specific schedule states. For 33 the responses were related to the cue or bar-release, were phasic and all-or-none. Ten others showed phasic responses with strengths that were proportional to the proximity of the rewarded trial. These latter responses are related to the increasing motivation inferred from the decreasing behavioral errors. Ten neurons had sustained responses beginning in the first trial and ending at or just before the last trial of each schedule. These two response types provide a means to predict the persistence needed to complete multitrial schedules successfully.
Supported by AIST/MITI; IRP/NIMH
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online.
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