Neuroscience 2002 Abstract
| Presentation Number: | 841.5 |
|---|---|
| Abstract Title: | Modulation of Cortical Sensorimotor Activities by Acupuncture: Preliminary Functional MRI Study at 3 Tesla. |
| Authors: |
Yoo, S. S.*1,3
; Kang, S. K.1
; Choi, G. S.4
; Chung, S. T.1
; Chu, M. J.1
; Lee, E. J.1
; Park, S. D.4
; Jeun, S. S.2
; Choe, B. Y.1
1Biomedical Engineering, The Catholic University of Korea, Seoul, Democratic People's Republic of Korea 2Neurosurgery, The Catholic University of Korea, Seoul, Democratic People's Republic of Korea 3Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 4Dong-Seo Oriental Medicine Hospital, Seoul, Democratic People's Republic of Korea |
| Primary Theme and Topics |
Sensory Systems - Tactile/Somatosensory -- Cortex imaging |
| Secondary Theme and Topics | Motor Systems<br />- Cortex and Thalamus<br />-- Imaging |
| Session: |
841. Tactile/somatosensory: cortex imaging II Poster |
| Presentation Time: | Thursday, November 7, 2002 8:00 AM-9:00 AM |
| Location: | Hall A2-B3 E-4 |
| Keywords: | STIMULATION, IMAGING, MAPPING |
We report a modulation of cortical sensorimotor activity by the acupuncture of GB34 acupoint (located behind the knee, often used for the treatment of hemiplagia). Using a 3T MR scanner, functional MRI(fMRI) was performed across seven normal volunteers (F:M=1:6, Mean Age=27) on two stimulation paradigms; (1) acupuncture manipulation and (2) stimulation of a sham point near the designated acupoint. Gradient-echo EPI sequence (TR/TE=2500/35msec; 24cm field-of-view, 64x64 matrix; 6mm thick) was used to image the whole brain. Each functional session was initiated without the needle insertion. At the 11th scan, the needle was inserted and twisted for 25 seconds at a rate of ~2Hz, followed by a pause for the duration of 25 seconds as a control state. This process was repeated four times. All subjects underwent the acupuncture fMRI session without pain sensation. From the random effect group analysis (p<0.01) using SPM99, bilateral sensorimotor areas (Brodmann's Areas (BA) 3,4,6 and 7) showed acupuncture-related MR signal contrast while only sensory areas were active during sham stimulation, suggestive of spatially dependent efficacy of acupuncture. In the absence of apparent hand motion (monitored by CCD camera), a dominant activation was observed in the left BA4 (Talairach coordinate x:y:z=-37:-22:62), close to the hand motor area ipsilateral to the site of the acupuncture (Left leg). Our findings provide preliminary evidence of cortical modulation by the administration of acupuncture.
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2002 Neuroscience Meeting Planner. Orlando, FL: Society for Neuroscience, 2002. Online.
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