Neuroscience 2004 Abstract
| Presentation Number: | 648.3 |
|---|---|
| Abstract Title: | Synchronous transition between two activity states of neurons in area TE of macaque monkeys. |
| Authors: |
Uchida, G.*1
; Fukuda, M.1
; Tanifuji, M.1
1Lab. for Integrative Neural Systems, Brain Sci. Inst., RIKEN, Wako-Shi, Japan |
| Primary Theme and Topics |
Sensory Systems - Vision -- Visual cortex: Neural coding |
| Session: |
648. Visual Cortex: Population Dynamics and Synchrony Poster |
| Presentation Time: | Tuesday, October 26, 2004 10:00 AM-11:00 AM |
| Location: | San Diego Convention Center - Hall A-H, Board # AA9 |
| Keywords: | SYNCHRONIZATION, CORRELATION , MEMBRANE POTENTIAL, SPIKE TRAIN |
In relation to object representation by neurons in area TE, we have examined synchronization of firing of TE neurons (Uchida, et al. SFN, 2002.). We showed that in 44% (25/57) of TE neuron pairs, a symmetrical broad peak (mean half peak width~125ms) appears in cross-correlogram of spike trains at 0 time delay. In this study, to explore origin of the broad peak, for each of the 25 neuron pairs we calculated auto-correlograms of the constituent neurons and directly compared them with cross-correlogram of the neurons. In 52% (13/25) of the neuron pairs, auto-correlograms of the constituent neurons consisted of a sharp peak at the center (0 time delay) and a gradual decay component from the center (For the rest of the pairs (n=12), one of the constituent neurons only had the sharp peak at the center). A regression analysis of the auto-correlograms revealed that this decay component is well fitted with an exponential function (time constant~120ms). This result is consistent with the model that a TE neuron takes two activity states, states with high and low firing activities, and the transition between these two states occurs in random. Next, we compared the auto- and the cross-correlograms for each of the 13 neuron pairs in which both constituent neurons had the gradual decay component. We found that the gradual decay components in the auto-correlograms are well overlapped with the broad peak in the cross-correlogram. Thus, we conclude (1) that neurons in area TE have two activity states and (2) that synchronous transition between two states for a pair of neurons causes broad peaks in cross-correlograms. The absence of a sharp peak in the cross-correlogram could be explained by no precise spike timing synchronization. The synchronous state transitions may be related to synchronous up-down state transitions of membrane potentials of neurons as reported for neurons in striatal and cat primary visual cortex.
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online.
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