Neuroscience 2000 Abstract
| Presentation Number: | 593.7 |
|---|---|
| Abstract Title: | Functional MRI of anesthetized monkeys using three dimensional structure from motion stimuli. |
| Authors: |
Muckli, L.*1
; Goebel, R.2
; Singer, W.1
; Munk, M. H. J.1
1Max-Planck-Institute for Brain Research, Frankfurt / M., Germany 2Psychology, University, Maastricht, The Netherlands |
| Primary Theme and Topics |
F. Sensory Systems - 80. Visual cortex: extrastriate |
| Session: |
593. Visual cortex: extrastriate--motion and depth Slide |
| Presentation Time: | Wednesday, November 8, 2000 9:30 AM-9:45 AM |
| Location: | Room 288 |
| Keywords: | VISION, FMRI, MONKEY, MT |
Functional magnetic resonance imaging (fMRI) has previously been used in humans to show functional separation between activation of dorsal and ventral visual areas using three dimensional structure from motion (SFM) stimuli (Naumer et al., Human Brain Mapping Abstr. 2000). We used identical stimuli to measure BOLD signals in ketamine anesthetized macaque monkeys (N=5). This imaging technique has recently been applied to monkeys anesthetized with isoflurane in a high magnetic field (4.7 T) scanner (Logothetis et al., 1999) and to awake monkeys in a standard 1.5T scanner (Vanduffel et al., Soc. Neurosci. Abst. 1998). Our fMRI study was performed at 1.5T using standard EPI sequences (Siemens Magnetom Vision, 8-16 slices, voxel size: 1.6 - 3.2 mm3, TR = 2-3 s). The head of the anesthetized monkeys was restrained in sphinx position with bolt implant and custom head holder or in supine position with cushions. Eye refraction was corrected with contact lenses. FMRI signals was analyzed using BrainVoyager 2000 including cortex-based independent component analysis (cbICA, Formisano et al., Soc. Neurosci. Abstr. 2000). Activity related to moving stimuli was found in the parietal part of the superior temporal sulcus (STS) of all monkeys. In two monkeys additional inferior temporal (IT) activation was found during the presentation of the 3d SFM stimuli (turning heads of monkeys). Our results demonstrate that it is possible to detect and discriminate specific activation profiles for motion and SFM stimuli in dorsal (STS) and ventral (IT) visual areas in anesthetized monkeys.
Supported by Max Planck Society
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online.
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