Neuroscience 2000 Abstract
| Presentation Number: | 464.38 |
|---|---|
| Abstract Title: | A functional MRI study of language components using a match-to-sample task. |
| Authors: |
Francis, W. S.*1
; Peterson, K.2
; Illes, J.3
; Gabrieli, J. D. E.3,4
1Dept of Psychology, University of Texas at El Paso, El Paso, TX 2Dept of Neurology, Stanford University, Stanford, CA 3Dept of Radiology, Stanford University, Stanford, CA 4Dept of Psychology, Stanford University, Stanford, CA |
| Primary Theme and Topics |
I. Neural Basis of Behavior - 103. Cognition: language |
| Secondary Theme and Topics | I. Neural Basis of Behavior<br />- 105. Cognition: higher functions |
| Session: |
464. Cognition: language II Poster |
| Presentation Time: | Tuesday, November 7, 2000 9:00 AM-10:00 AM |
| Location: | Hall G-J |
| Keywords: | LANGUAGE, FMRI |
Linguistic processing is a complex skill with several dissociable components, including semantic, phonological, and syntactic processing. The goal of the present study was to compare and contrast the patterns of cortical activity associated with each of these processes. Twelve healthy young adults were scanned while performing match-to-sample tasks meant to elicit three different types of language processing. The semantic task required choosing a synonym, the phonological task required choosing a rhyme from among two words ending with the same sequence of letters, and the syntactic task required choosing a verb to agree in number with a singular or plural noun. Each of these tasks was compared to a control task of choosing an identical match in an alternating block sequence. Thus the format of the stimulus and the format of the response remained constant across all conditions, and only the linguistic basis of the decision varied. Imaging was performed using a 1.5 T whole-body MRI scanner with a full head coil. The entire brain was imaged in 29 coronal planes (through-plane resolution = 6 mm, in-plane resolution = 3.75 mm). The task alternated every 30 sec (TR = 3 sec, TE = 40 ms). Each of the tasks of interest elicited increases in activation relative to the control task in prefrontal and other regions. The specific cortical regions implicated depended on the particular language component.
Supported by a Stanford University Department of Neurology seed grant and NIH/NIA grant AG12995.
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online.
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