Neuroscience 2000 Abstract
| Presentation Number: | 464.16 |
|---|---|
| Abstract Title: | MRI measurement of the planum temporale: implications from an interlaboratory study. |
| Authors: |
Leonard, C. M.*1
; Kigar, D. L.2
; Black, S. E.3
; Bronskill, M. J.3
; Witelson, S. F.2
1Dept Neurosci, Univ Of Florida Brain Inst, Gainesville, FL 2Psychiat & Behav Neurosci, McMaster Univ, Hamilton, Canada 3Neurol & Imaging Research, Sunnybrook & Women's College Hosp., Toronto, Canada |
| Primary Theme and Topics |
I. Neural Basis of Behavior - 103. Cognition: language |
| Session: |
464. Cognition: language II Poster |
| Presentation Time: | Tuesday, November 7, 2000 11:00 AM-12:00 PM |
| Location: | Hall G-J |
| Keywords: | magnetic resonance imaging methodology, language, lateralization, cognitive |
Boundaries of specific gyri are often ambiguous, even on postmortem examination. This study addressed the reliability of MRI measurement between two labs using different methodologies for one frequently studied region, the planum temporale (PT). Scans were obtained for 40 normal men, aged 18-35 yr, who also had cognitive testing. The whole brain was scanned in 1.3 mm contiguous slices using a 1.5T MR imager (GE). The length of the horizontal segment of PT (HPT) was measured, extending from Heschl's main transverse sulcus (point H) to the point of posterior bifurcation of the Sylvian fissure (SF) or the end of the SF (point B). Both labs studied the same set of 40 scans and used the same definition of HPT (Witelson & Kigar, JCN, 1992). Lab 1 used all relevant slices in 3 planes, to locate the x, y, and z coordinates of points H and B and obtained the distance of HB. Lab 2 obtained the length of the tracing of the exposed surface of HB on sagittal slices (as in Leonard et al., Arch Neurol, 1993). Both labs obtained the typical larger left PT and mean laterality scores were similar. However, intraclass correlations done to assess the consistency of measurements for each case between labs revealed discrepancies. A few cases revealed very different scores. These results may shed light on inconsistencies among published studies and indicate potential pitfalls in correlational analyses between structure and cognition.
Supported by MRC10610,NS18954,The Albert Einstein/Irving Zucker Research Program (SFW); GE Medical Systems (MJB)
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online.
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