Neuroscience 2004 Abstract
| Presentation Number: | 413.10 |
|---|---|
| Abstract Title: | A low dose of delta-9-tetrahydrocannabinol (THC) enhances sucrose palatability when administered 120-min, but not 30- or 60-min, prior to a taste reactivity test. |
| Authors: |
Jarrett, M.*1
; Limebeer, C. L.1
; Parker, L. A.1
1Psychology, Wilfrid Laurier Univ., Waterloo, Canada |
| Primary Theme and Topics |
Cognition and Behavior - Human and Animal Cognition and Behavior -- Emotional learning & memory systems and modulation of memory |
| Secondary Theme and Topics | Sensory Systems<br />- Chemical senses<br />-- Taste |
| Session: |
413. Taste II Poster |
| Presentation Time: | Monday, October 25, 2004 9:00 AM-10:00 AM |
| Location: | San Diego Convention Center - Hall A-H, Board # V3 |
| Keywords: | Rat, Feeding, Taste, Drug Reward |
Considerable anecdotal reports suggest that marijuana enhances palatability, however there has been little direct experimental evidence for these claims. The taste reactivity (TR) test is a direct measure of palatability in rats. The taste reactivity (TR) test was used to evaluate the potential of THC to modify sucrose palatability as measured by the frequency of tongue protrusions. On each of the 9 test trials, rats were injected with either THC (0.5 mg/kg) or vehicle 30, 60 or 120 minutes prior to receiving a 5 min intraoral infusion of 2%, 10% and 32% sucrose solution. The TR test revealed that at 120 min post-injection THC increased the palatability of sucrose solution, regardless of the concentration. Current experiments are investigating the effects of THC on quinine palatability using the TR test.
Supported by Natural Sciences and Engineeering Research Council of Canada
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online.
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