Neuroscience 2005 Abstract
| Presentation Number: | 421.6 |
|---|---|
| Abstract Title: | The effect of THC and AM251 on sucrose and quinine palatability: a direct measure through taste reactivity. |
| Authors: |
Jarrett, M. M.*1
; Parker, L. A.1
1Psychology, Wilfrid Laurier Univ., Waterloo, Canada |
| Primary Theme and Topics |
Cognition and Behavior - Motivation and Emotion -- Reward |
| Session: |
421. Reward: Alcohol, Cannaniboids, and Morphine Poster |
| Presentation Time: | Monday, November 14, 2005 9:00 AM-10:00 AM |
| Location: | Washington Convention Center - Hall A-C, Board # KK21 |
| Keywords: | Cannabinoid, palatability, THC, taste |
Anecdotal reports suggest that cannabinoid agonists enhance palatability and antagonists reduce palatability; however there has been little direct experimental evidence for these claims. The taste reactivity (TR) test is a direct measure of palatability in rats. In Experiments 1 and 2, the taste reactivity (TR) test was used to evaluate the potential of delta-9-tetrahydrocannabinol (THC) to modify both sucrose and quinine palatability. The TR test revealed that THC increases the palatability of sucrose solutions at 120 min post-injection, regardless of the concentration. THC also decreased the aversiveness of the quinine solution regardless of the post-injection interval. In Experiment 3, the taste reactivity (TR) test was used to evaluate the potential of AM251 to modify both sucrose and quinine palatability. The TR test revealed that AM251 decreased the palatability of sucrose regardless of the post-injection interval. Surprisingly, AM251 had no effect on quinine palatability.
Supported by NSERC
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online.
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