Neuroscience 2001 Abstract
Presentation Number: | 456.12 |
---|---|
Abstract Title: | functional magnetic resonance imaging of the brain during deception. |
Authors: |
Langleben, D. D.*1
; Schroeder, L.1
; Maldjian, J.1
; Gur, R. C.1
; McDonald, S.1
; O'Brien, C. P.1
; Childress, A. R.1
1University of Pennsylvania, Philadephia, PA |
Primary Theme and Topics |
Cognition and Behavior - Human Cognition and Behavior -- Other higher functions |
Secondary Theme and Topics | Cognition and Behavior<br />- Human Cognition and Behavior<br />-- Attention |
Session: |
456. Human cognition and behavior: executive function--reasoning and problem solving II Slide |
Presentation Time: | Tuesday, November 13, 2001 10:45 AM-11:00 AM |
Location: | Room 5B |
Keywords: | Guilty Knowledge Task, MRI, cingulate, attention |
Background: Deception is a cognitive phenomenon with important practical implications. Existence of a correlation between the P-300 component of evoked brain potentials and deception suggests that the cognitive distinction between truth and lie could be associated with differences in local brain activity. The guilty knowledge task (GKT) has been used to simulate deception under laboratory and field conditions. Functional Magnetic Resonance Imaging (fMRI) allows high-resolution study of changes in regional cerebral blood flow (rCBF) during cognition. We used fMRI to identify brain regions differentially activated by deceptive and truthful responses on the GKT.
Methods: fMRI was performed in 23 normal subjects during the GKT. The amplitude and location of fMRI signal during and after deceptive and truthful responses were recorded. After exclusion of five subjects for task errors and motion artifact, data was analyzed for rCBF differences between truthful and deceptive responses.
Results: Increased rCBF was seen in the anterior cingulate and the adjacent right superior frontal gyrus after deceptive responses.
Conclusions: Functional anatomic difference between simulated truth and deception conditions suggests that there is a localized brain correlate of deception. Anterior cingulate activation is associated with response inhibition and error monitoring, suggesting that they are among the basic elements of the cognitive mechanism of deception.
Methods: fMRI was performed in 23 normal subjects during the GKT. The amplitude and location of fMRI signal during and after deceptive and truthful responses were recorded. After exclusion of five subjects for task errors and motion artifact, data was analyzed for rCBF differences between truthful and deceptive responses.
Results: Increased rCBF was seen in the anterior cingulate and the adjacent right superior frontal gyrus after deceptive responses.
Conclusions: Functional anatomic difference between simulated truth and deception conditions suggests that there is a localized brain correlate of deception. Anterior cingulate activation is associated with response inhibition and error monitoring, suggesting that they are among the basic elements of the cognitive mechanism of deception.
Supported by NIDA R01 DA 10241
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2001 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2001. Online.
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