Neuroscience 2005 Abstract
| Presentation Number: | 410.9 |
|---|---|
| Abstract Title: | The temporal pole and memory in humans: an MRI, anatomical, and cytoarchitectonic study. |
| Authors: |
Blaizot, X.*1,2
; Martinez-Marcos, A.1
; Constans, J. M.2
; Pro, P.1
; Mohedano, A.1
; Cebada, S.1
; Artacho-Pérula, E.1
; Marcos, P.1
; Arroyo-Jiménez, M.1
; Insausti, R.1
1Anatomy, Univ. Castilla-La Mancha, Albacete, Spain 2France, Av de Almansa, 02006, |
| Primary Theme and Topics |
Cognition and Behavior - Human Cognition, Behavior, and Anatomy -- Anatomy |
| Secondary Theme and Topics | Sensory and Motor Systems<br />- Comparative Anatomy and Evolution |
| Session: |
410. Anatomy and Individual Differences Poster |
| Presentation Time: | Monday, November 14, 2005 8:00 AM-9:00 AM |
| Location: | Washington Convention Center - Hall A-C, Board # EE20 |
| Keywords: | perirhinal cortex, comparative anatomy, declarative memory, neural basis |
The parahippocampal gyrus, located in the medial temporal lobe, is a key brain area in memory processing. Several recent functional studies performed either in humans or in non human primates have revealed the implication of its rostral part, the temporal pole in declarative memory. The temporal pole is located rostral to the entorhinal and piriform cortices. We have analyzed the general organization of the temporal pole in humans from MR images and histological slices, on both, macroscopic and cytoarchitectonic aspects. This work was also performed to provide anatomical landmarks to facilitate and precise the brain structures implicated in memory as revealed by functional MRI and PET activation studies.
The basic analysis has been performed from the brain of 9 healthy people. The brains were serially sectioned and stained with thionin to determine cytarchitectonic boundaries. T1-weighted MR images obtained in controls were analyzed in reference to the neighboring anatomical landmarks.
The features of the temporal pole in humans will be described in details together with the macroscopic criteria as determined on MR images. Similar topographical relationships were observed in the organization of the temporal pole in humans as compared to non human primates. However, its extent in humans does represent a higher proportion of the surface of the parahippocampal gyrus as revealed by the two-dimensional unfolded maps and its neuronal organization appears more diffused with less defined layers. The microscopic analysis revealed that the temporal pole is made up of two subareas, 36pl and 36pm. Both areas present 6 layers with their own characteristics. These data suggest that the temporal pole specialization may contribute to declarative memory development.
The basic analysis has been performed from the brain of 9 healthy people. The brains were serially sectioned and stained with thionin to determine cytarchitectonic boundaries. T1-weighted MR images obtained in controls were analyzed in reference to the neighboring anatomical landmarks.
The features of the temporal pole in humans will be described in details together with the macroscopic criteria as determined on MR images. Similar topographical relationships were observed in the organization of the temporal pole in humans as compared to non human primates. However, its extent in humans does represent a higher proportion of the surface of the parahippocampal gyrus as revealed by the two-dimensional unfolded maps and its neuronal organization appears more diffused with less defined layers. The microscopic analysis revealed that the temporal pole is made up of two subareas, 36pl and 36pm. Both areas present 6 layers with their own characteristics. These data suggest that the temporal pole specialization may contribute to declarative memory development.
Supported by Junta de Comunidades de Castilla-La Mancha, Consejería de Sanidad
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online.
Copyright © 2005-2025 Society for Neuroscience; all rights reserved. Permission to republish any abstract or part of any abstract in any form must be obtained in writing by SfN office prior to publication.
