Neuroscience 2005 Abstract
| Presentation Number: | 333.6 |
|---|---|
| Abstract Title: | Incidence of microbleeds in moyamoya disease: analysis with 3 tesla magnetic resonance imaging study. |
| Authors: |
Kikuta, K.*1
; Takagi, Y.1
; Nozaki, K.1
; Hanakawa, T.2
; Okada, T.3
; Fushimi, Y.3
; Hidenao, F.2
; Hashimoto, N.1
1 Department of Neurosurgery, Kyoto Univ. Graduate School of Medicine, Kyoto, Japan 2Human Brain Research Center, Kyoto Univ. Graduate School of Medicine, Kyoto, Japan 3Department of Nuclear Medicine and Diagnostic Radiology, Kyoto Univ. Graduate School of Medicine, Kyoto, Japan |
| Primary Theme and Topics |
Disorders of the Nervous System - Ischemia -- Human studies and animal models |
| Session: |
333. Hypoxia/Ischemia: Human Studies and Animal Models Poster |
| Presentation Time: | Sunday, November 13, 2005 2:00 PM-3:00 PM |
| Location: | Washington Convention Center - Hall A-C, Board # UU53 |
| Keywords: | moyamoya, microbleeds, T2*-weighted, hemorrhage |
Object Incidence of silent microbleeds (MBs) in patients with moyamoya disease (MMD) was investigated using 3-tesla (3T) MR unit.
Methods We retrospectively examined incidence of silent MBs in twenty-five patients among 63 patients hospitalized with MMD between 1999 and 2004 by gradient-echo T2*-weighted images using 3-tesla (3T) and 1.5T MR units. There were five men and twenty women, ranging in age from 17 to 66 years old (mean 41+14 years old). Eighteen patients were diagnosed with ischemic MMD and seven patients with hemorrhagic MMD. Incidence of MBs was also evaluated with the same 3T MR unit in thirty-four healthy volunteers including seven men and twenty-seven women, ranging in age from 18 to 71 years old (mean 33+12 years old). Silent MBs could be fond in eleven patients (44 %) by 3T MR unit, while they were detected in seven patients (28%) by1.5T unit. At the 3T study of the healthy individuals, MBs were found in two patients (5.8%). Incidence of MBs was significantly higher in the patients with MMD than in healthy individuals at 3T study. Silent MBs were found in eight (44 %) of the eighteen patients with ischemic MMD and three of the seven patients (43 %) with hemorrhagic MMD.
Conclusions MBs can be found significantly more common in patients with MMD than in healthy individuals regardless of the onset type. Evaluation of MBs with T2*-weighted 3T MR imaging might contribute to the treatment of MMD.
Methods We retrospectively examined incidence of silent MBs in twenty-five patients among 63 patients hospitalized with MMD between 1999 and 2004 by gradient-echo T2*-weighted images using 3-tesla (3T) and 1.5T MR units. There were five men and twenty women, ranging in age from 17 to 66 years old (mean 41+14 years old). Eighteen patients were diagnosed with ischemic MMD and seven patients with hemorrhagic MMD. Incidence of MBs was also evaluated with the same 3T MR unit in thirty-four healthy volunteers including seven men and twenty-seven women, ranging in age from 18 to 71 years old (mean 33+12 years old). Silent MBs could be fond in eleven patients (44 %) by 3T MR unit, while they were detected in seven patients (28%) by1.5T unit. At the 3T study of the healthy individuals, MBs were found in two patients (5.8%). Incidence of MBs was significantly higher in the patients with MMD than in healthy individuals at 3T study. Silent MBs were found in eight (44 %) of the eighteen patients with ischemic MMD and three of the seven patients (43 %) with hemorrhagic MMD.
Conclusions MBs can be found significantly more common in patients with MMD than in healthy individuals regardless of the onset type. Evaluation of MBs with T2*-weighted 3T MR imaging might contribute to the treatment of MMD.
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2005 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience, 2005. Online.
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