Neuroscience 2004 Abstract
| Presentation Number: | 240.12 |
|---|---|
| Abstract Title: | MRI analysis of lesion extension at different times following surgery. |
| Authors: |
Russell, M. I.*2
; Castiglioni, J. A.2
; Steele-Russell, I.1,2
; Tarver, C. C.3
; Wright, S. M.3
1Anat. & NeuroBiology, TAMU HSC, College Station, TX 2Psychiatry & Behavioral Sci. Sensory Neurosci. Lab., TAMU HSC, College Station, TX 3TX, TAMU College of Medicine, 77843-4458, |
| Primary Theme and Topics |
Techniques in Neuroscience - Staining, tracing and imaging techniques |
| Secondary Theme and Topics | Cognition and Behavior<br />- Human and Animal Cognition and Behavior<br />-- Learning & memory: Physiology and imaging |
| Session: |
240. Imaging Techniques: fMRI, BOLD, and Other Poster |
| Presentation Time: | Sunday, October 24, 2004 11:00 AM-12:00 PM |
| Location: | San Diego Convention Center - Hall A-H, Board # GGG19 |
| Keywords: | Rabbit, MRI, Imaging, Corpus Callosum |
The rabbit is an ideal animal for fMRI imaging research. It is uniquely tolerant of restraint for prolonged time periods without the need for any anaesthetic to immobilize the animal. The visual pathways and central mechanisms of both pattern and movement vision are well explored. In addition the associative conditioning of the rabbit nictitating membrane has long been a major animal model for studying neural mechanisms of associative learning. The purpose of the present study is to determine the concordance between MRI assessment of the extent of experimentally induced brain lesions with postmortem histological reconstruction of the lesions. Using sterile procedure discrete sections of the corpus callosum were made in the rabbit brain. Assessment of tissue damage was undertaken both after 1 hour and 72 hours following surgery. Magnetic field images (6 Tesla) of lesion damage are described and compared with detailed histological reconstruction for both fiber and cellular damage.
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2004 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2004. Online.
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