Neuroscience 2003 Abstract
| Presentation Number: | 94.5 |
|---|---|
| Abstract Title: | Limbic system-associated membrane protein (LAMP) immunohistochemistry reveals similarities in the visual and auditory systems between species. |
| Authors: |
Yamamoto, K.*1
; Laverghetta, A. V.1
; Karten, H. J.2
; Reiner, A. J.1
1Dept. of Anat. & NeuroBiol., Univ. of Tennessee Hlth. Sci. Ctr., Memphis, TN 2CA, 855 Monroe Ave., 38163, |
| Primary Theme and Topics |
Cognition and Behavior - Neuroethology -- Comparative anatomy & evolution |
| Secondary Theme and Topics | Sensory Systems<br />- Vision<br />-- Subcortical visual pathways |
| Session: |
94. Neuroethology: Comparative Anatomy & Evolution Poster |
| Presentation Time: | Saturday, November 8, 2003 1:00 PM-2:00 PM |
| Location: | Morial Convention Center - Hall F-I, Board # FF1 |
| Keywords: | evolution, avian, thalamus, midbrain |
Limbic system-associated membrane protein (LAMP) is a cell adhesion molecule expressed mainly in the limbic system and it plays a role in axonal patterning during brain development. LAMP was originally found in mammals, but our previous study on LAMP distribution in pigeon brain (Yamamoto & Reiner, SFN 31st annual meeting abstract, 2001) showed that LAMP is present even in non-mammalian species. In this study, we performed immunohistochemistry for LAMP in rats, ground squirrels, pigeons, and zebra finches to compare visual and auditory nuclei in the thalamus and midbrain. As in previous studies, LAMP labeling was mainly found in midline limbic structures in all species, but there were several non-limbic visual structures that showed LAMP labeling. In the midbrain, both the avian optic tectum and upper layers of the mammalian superior colliculus, which contain comparable cell types, were LAMP-rich. In the thalamus, the avian nu rotundus (Rt), which receives afferent projections from the optic tectum, was rich in LAMP. The mammalian thalamic nucleus receiving projections from upper superior colliculus, the lateral posterior nu (LP) in rats and the caudal pulvinar in ground squirrels, was also LAMP-rich. Although an alternative hypothesis suggests that mammalian posterior nu of the thalamus (Po) might be homologous to the avian Rt (Davila et al., JCN, 2000), Po was LAMP-poor. Thus, our LAMP labeling suggests that the LP/caudal pulvinar, instead of Po, is likely to be homologous to the avian Rt. In contrast to visual nuclei, auditory nuclei in the midbrain (inferior colliculus in mammals and nu mesencephalicus lateralis, pars dorsalis in birds) and in the thalamus (the ventral medial geniculate nu in mammals and nu ovoidalis in birds) were LAMP-poor.
Supported by NS19620 (AR)/NS24560 (HJK)
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2003 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2003. Online.
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