Neuroscience 2000 Abstract
Presentation Number: | 643.5 |
---|---|
Abstract Title: | A kinematic model of <I>Aplysia</I> swallowing based on MRI imaging. |
Authors: |
Sutton, G. P.*1
; Drushel, R. F.2
; Neustadter, D. M.3,5
; Crago, P. E.3
; Chiel, H. J.2,4
1Mechanical Engineering, Case Western Reserve University, Cleveland, OH 2Biology, Case Western Reserve University, Cleveland, OH 3Biomedical Engineering, Case Western Reserve University, Cleveland, OH 4Neurosciences, Case Western Reserve University, Cleveland, OH 5GE Medical Systems, Haifa, Israel |
Primary Theme and Topics |
G. Motor Systems and Sensorimotor Integration - 95. Invertebrate motor and sensory systems |
Secondary Theme and Topics | I. Neural Basis of Behavior<br />- 114. Invertebrate learning and behavior |
Session: |
643. Invertebrate motor and sensory systems III Poster |
Presentation Time: | Wednesday, November 8, 2000 8:00 AM-9:00 AM |
Location: | Hall G-J |
Keywords: | BIOMECHANICS, FEEDING, KINEMATICS, MODELING |
In order to understand the kinematics of the musculature controlling feeding in the marine mollusk Aplysia californica, we have developed a series of increasingly realistic kinematic models of the feeding apparatus, the buccal mass (Drushel et al., JEB, 1998; Chiel et al., Soc. Neurosci. Abstr., 1998, 1999). Using high spatial resolution MRI scans of freshly dissected buccal masses, a realistic external shape of the radula/odontophore at rest has been determined, which is approximated by modified ellipsoid octants. The surface of the radula is approximated by two planes that intersect the volume of the odontophore. By extracting parameters from high temporal resolution MRI taken of the buccal mass during swallowing movements in intact animals, it is possible to generate realistic shapes and positions for the radula/odontophore during the entire swallowing cycle, subject to the biological constraints that the total surface of the radula and the total volume of the odontophore are kept constant. To validate predictions of the model, we are measuring dorso-ventral views of the buccal mass during swallowing from juvenile, transilluminated animals (Drushel et al., JEB 1997) and comparing them to those predicted by the kinematic model. We are also comparing medio-lateral views generated by the model to midsagittal views obtained in intact animals using high temporal resolution MRI. The more realistic model of the radula/odontophore makes it possible to predict the lengths and velocities of muscles intrinsic to it (e.g., I7) as well as of muscles surrounding it (e.g., I2 and I1/I3).
Supported by Whitehall Foundation, NSF
Sample Citation:
[Authors]. [Abstract Title]. Program No. XXX.XX. 2000 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2000. Online.
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