Thank you for attending Neuroscience 2019!

$$table_{68DE6E3A-D99A-4BEA-83F2-81A22578DBAC}$$ Ricardo Araneda will discuss his journey as a scientist growing up in Patagonia, Chile, and migrating north following scents of discovery. Olfaction has an inherent complexity due to vast number of olfact...

Thank you for attending Neuroscience 2022.

On Thursday, March 17, over 60 neuroscientists will take their message to Congress for SfN’s 10thCapitol Hill Day »

Game theorists often quote the story of Sherlock Holmes fleeing London by train in direction of Dover, and applying the following recursive reasoning: if he were to continue the journey without giving thought to his pursuers (order-one strategy), then surely Moriarty would find out and follow him to

General Attendee Abstract Presenters Exhibitors

Neuroscience 2025 Register Now for Neuroscience 2025!

The Society for Neuroscience (SfN) and the Tianqiao and Chrissy Chen Institute announced a new partnership to support promising early career neuroscientists in their professional development and publishing trajectories.

Sleep-wake states bi-directionally interact with epilepsy and seizures, but the mechanisms are unknown. A barrier to comprehensive characterization and the study of mechanisms has been the difficulty of annotating large chronic recording datasets. To overcome this barrier, we sought to develop an automated method of classifying sleep-wake states, seizures, and the post-ictal state in mice ranging from controls to mice with severe epilepsy with accompanying background EEG abnormalities. We utilized a large dataset of recordings, including EMG, EEG, and hippocampal local field potentials, from control and intra-amygdala kainic acid-treated mice. We found that an existing sleep-wake classifier performed poorly, even after retraining. A support vector machine, relying on typically used scoring parameters, also performed below our benchmark. We then trained and evaluated several multi-layer neural network architectures and found that a bidirectional long short-term memory-based model performed best. This ‘Sleep...

The environment experienced by children, such as exposure to chronic early life adversity (ELA), increases lifespan brain disorder risk. The mechanisms that link ELA exposure to functional brain disruptions are not well understood. A limited-bedding and nesting paradigm, in which ELA is induced in mouse pups over the first postnatal week through disruption of maternal care, is characterized by limited resources, environment unpredictability, and disruption of reward and cognitive behaviors. Studies using this model demonstrated sex-selective alterations in hippocampal mitochondrial-associated proteins in response to ELA compared with care as usual (CAU). Further, oxidative phosphorylation (OXPHOS) capacity and complex I activity are increased in ELA juveniles, yet decreased in adults, with the impact of ELA moderated by sex in adults. Given that altered mitochondrial function is a key mediator in metabolic adaptations, the goal of the present study was to evaluate the possibility of reversing mitochondrial...