The Society for Neuroscience (SfN) announced the winners of the achievement awards during Neuroscience 2010. “The achievement awards provide SfN members with a chance to recognize colleagues who have demonstrated a profound commitment to career achievement and the advancement of women in neuroscience,” said Michael E. Goldberg, MD, president of SfN.

There is increasing interest in using marmosets for animal studies in neuroscience. Several technologies such as neural tracing and genetic manipulation are recently available for this species, however, non-invasive imaging technique is not well establi...

IntroductionRecent advances in the field of magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) in particular, have enabled detection of pathology-specific features such as microstructural changes in the white matter’s (WM) axons and mye...

Resting-state functional connectivity (rsFC) magnetic resonance imaging (MRI) represents a powerful method for illuminating brain network function. Moreover, it has a particular relevance for posttraumatic stress disorder (PTSD), where abnormalities in ...

Advances in magnetic resonance imaging (MRI) and computational analysis technology enable comparisons among various primate brains in a three-dimensional electronic format. Results from comparative studies provide information about common features acros...

Down syndrome (DS) is a major cause of genetic imbalances causing brain disease throughout the lifespan: intellectual disabilities due to developmental perturbations in the young through premature aging and Alzheimer’s disease (AD) in the old. Because t...

Background The deficits of brain structure in children with developmental dyslexia (DD children) still remain unknown.Updated magnetic resonance imaging (MRI) techniques have provided multiple new possibilities to study reading-relevant neural networks ...

Human magnetic resonance imaging (MRI) studies have associated depression with alterations in the function, morphology and connectivity of a distributed corticolimbic circuitry including the amygdala, hippocampus, and prefrontal cortex. In parallel, str...

Spontaneous fluctuations in Blood Oxygen Level Dependent (BOLD) functional Magnetic Resonance Imaging (MRI) signals are used to infer functional connectivity. However, the implicit assumption that spontaneous fluctuations in blood oxygenation are relate...

Although significant strides have been made using high-field fMRI to study brain activity in primates (e.g. Logothetis, 2003, 2002), many of these studies have employed anesthesia and paralytics which can significantly affect the BOLD response (Leopold et al., 2002). To better approximate the conditions under which human data is collected and to conduct oculomotor studies, we have recently developed techniques to acquire fMRI data at 4.7T using alert, behaving rhesus monkeys. To optimize ergonomics, a 60-cm bore, vertically oriented, superconducting magnet (Magnex) with a Varian console is used. Head stabilization is achieved through a stereotaxically-placed, polyetheretherketon superstructure attached to the skull with MRI-compatible ceramic screws. Monkeys are trained to fixate and/or track targets on a visual display system (Avotec) while the position of each eye is monitored (SensorMotoric Instruments). A successive approximation training schedule is then used to acclimate the animals to the environmen...